If a parent on the proband is thought to hold the pathogenic variant discovered while in the proband, the risk on the sibs of inheriting the pathogenic variant is 50%. Because of lowered penetrance, sibs who inherit the pathogenic variant might or might not acquire aHUS (see Penetrance). As We've https://industrialchillerhire76532.blogacep.com/37979708/ahu-hire-fundamentals-explained